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Managing cortisol levels and balancing the HPA axis are key for establishing a healthy stress response.*
The hypothalamic-pituitary-adrenal (HPA) axis helps maintain hormonal homeostasis during times of stress. Cortisol is produced by the adrenal cortex and plays an important role in regulating energy metabolism, heart rate, appetite, and immune function. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact. Typically, cortisol follows a circadian rhythm, peaking in the morning with a gradual decline throughout the day. However, during times of stress, cortisol is continuously produced and can impact whole-body wellness.
Our best-selling Cortisol Manager contains proprietary blends of Sensoril brand ashwagandha extract and L-theanine and of Magnolia and epimedium extracts, as well as phosphatidylserine, and is designed to:
Balance cortisol levels*
Help reduce stress*
Promote relaxation to support restful sleep*
Integrative Therapeutics’ HPA Adapt combines key adaptogenic herbs to help the body manage both mental and physical stress.*
What is this product designed to support?
Cortisol Manager is formulated to help support a healthy stress response and balance cortisol levels.* It combines ingredients such as ashwagandha extract and L-theanine to promote relaxation to support restful sleep.*
Who should take this product?
This product is intended for adults looking to support a healthy response to everyday stress and promote relaxation and calm to support restful sleep with ongoing use.* Do not use if you
are pregnant or nursing.
How should this product be taken?
Each bottle contains 30 tablets, which equals 15 servings when taken as directed (2 tablets per serving). Always follow the suggested use instructions on the label unless otherwise directed by your healthcare professional.
Is this product eligible for subscription orders?
Yes, this product is available through Amazon’s Subscribe & Save program. Delivery frequency can be adjusted within your Amazon account settings to better fit your needs.
What are similar products from Integrative Therapeutics?
For daytime support, consider HPA Adapt for stress-related fatigue support*; L-Theanine for calm and relaxation support*; or Tri-Magnesium to support a healthy response to stress.*
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Customer Reviews
4.3 out of 5 stars 10,421
4.5 out of 5 stars 1,962
4.6 out of 5 stars 1,372
4.6 out of 5 stars 1,555
4.4 out of 5 stars 2,145
4.5 out of 5 stars 444
Price
$26.75$26.75
$28.50$28.50
$39.50$39.50
$22.00$22.00
$37.50$37.50
$49.25$49.25
Serving Size
2 tablets
2 capsules
4 capsules
2 capsules
1 softgel
1 softgel
Count
30 tablets
30 capsules
120 capsules
60 capsules
60 softgels
60 softgels
Gluten Free
✔
✔
✔
✔
✔
✔
Key Ingredients
Ashwagandha + L-Theanine
Ashwagandha + L-Theanine
Adaptogenic herbal blend
L-Theanine
Lavender oil (WS 1265)
Phosphatidylserine
Product Benefits
Cortisol & stress support
Cortisol & stress support
Adaptogenic stress support
Calm & Relaxation support
Calm & sleep support
Brain & stress support
Is Discontinued By Manufacturer : No
Product Dimensions : 2.22 x 2.22 x 3.95 inches; 1.6 ounces
Item model number : 871791003811
Date First Available : January 2, 2009
Manufacturer : Integrative Therapeutics
ASIN : B002D2JYYG
Best Sellers Rank: #511 in Health & Household (See Top 100 in Health & Household) #2 in Adrenal Extract Nutritional Supplements
Customer Reviews: 4.3 4.3 out of 5 stars (10,421) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Best Overall Ashwagandha Supplement*: For stress support, Cortisol Manager has been voted best overall Ashwagandha supplement as seen in Vogue*; it helps support balanced cortisol levels and a healthy response to everyday stress*
Relaxation Support*: Supports relaxation and calm to support restful sleep*
Supports Restful Sleep During Stress*: With ongoing use, this supplement with L-theanine and ashwagandha helps ease occasional sleeplessness disrupted by stress*
Integrative Therapeutics Cortisol Manager: Cortisol Manager does not contain gluten, wheat, or dairy
About Integrative Therapeutics: For over 25 years, patients and clinicians have trusted us for our dedication to quality, potency, and accuracy; transparency around our sourcing and manufacturing processes is part of our quality promise to you
8 reviews for Integrative Therapeutics Cortisol Manager – Balance Cortisol & Support Relaxation for Restful Sleep* – Includes Ashwagandha & L-Theanine for Confidence with Less Stress* – 30 Tablets (15 Servings)
Add a review
$26.75
jessica finson –
Relaxed and weightloss
Absolutely amazing! Since I’ve started taking these, I’ve ordered two bottles. I have noticed a drastic difference one I’m starting to lose weight again. I have energy and motivation. I’m sleeping through the night. I’m no longer on edge in any time that I feel like my work life or family life has been too stressful. I take the recommended dose of two and when I wake up the next day, I feel so much better life-changing. I’m more relaxed and present in my everyday life.
Sheila Ruark –
Beneficial Product
This is the first time I’ve tried this product and I’m happy that I did. I started taking it the minute it arrived (arrived at bedtime). I slept 8 hours and VeriFit watch gave me a Perfect score for my sleep pattern. I had so much energy the next day that I took it to the back yard to do some difficult yard work. I also felt calm, relaxed, and had no food cravings. I slept 8 hours and 45 minutes the second night taking it and woke up feeling refreshed with another Perfect score on my VeriFit watch. I even watched my scale go down a pound. I couldn’t be happier with these results. I can’t wait to see what happens after 30+ days of taking it.
Angela T –
Sleeping like a baby again!
I wished I had found these supplements a lot sooner. They work better than melatonin. With Melatonin I kept waking up 2 to 3 times a night. Cortisol Manager stopped my 3 AM cortisol spikes. I had to adjust my how I take them thanks to AI. I take one at 7p.m. and my next one 30 mins before I go to sleep. I also take a spoonful of almond butter or eat a boil egg right before I go to sleep. Taking a proteins snack right before bed helps your body deal with blood sugar drops while you are sleeping. Great supplements that actually work. I wake up without feel tired. I am sleeping like a baby.
JASON C BUDDENBERG –
Good start
I’m a combat vet and I think I’ve had high cortisol and everything that goes with that for decades.First week of taking this supplement and I’ve had a bit of a headache at night, but better sleep, more calm during the day, and I’ve had some relief of my joint and tendon pain.Hoping to lose some of my gut and lower my blood pressure over the coming months.
Jeronimo’s Mom –
Best Supplement I have bought in a while
Best supplement I have bought in a while. I have been able to fall asleep right away & most importantly, remain asleep. I had not had a good night’s sleep in forever. This supplement has done the trick. I am a week in. Let’s see if it continues to work, but so far so good. This definitely works for anyone who endures a lot of stress & happens to have sleep issues.
jannaL –
Helps Keep Stress in Check
Integrative Therapeutics Cortisol Manager has been a noticeable help in managing my daily stress. I’ve been taking it consistently, and I feel more balanced, focused, and calmer throughout the day. I appreciate that it uses natural ingredients to support healthy cortisol levels, rather than relying on stimulants or harsh chemicals.The capsules are easy to take daily , and I’ve experienced no negative side effects. Over time, I’ve noticed improved energy in the afternoons and a better ability to handle stressful situations. I have it on auto ship.
Amanda –
Really wanted to love it….
Edit: April 7, 2025The seller contacted me and offered me a refund due to my experience. They did not ask me to change my rating, they just wanted me to be happy. I chose this brand because they are quality and trusted. This further underlines that, and they’ve gained a customer for life (but for a different product)! I added a star based on this. Again, they did not ask me to change my rating.Wanted to love it… but I had to stop after about 10 days. This supplement seemed like the perfect blend. It did make me sleepy, but weirdly, I slept TERRIBLY. I was sleepy but also wired? After about 5 days I noticed some spotting which was weird. I take progesterone at night for sleep and to help with perimenopause symptoms. I haven’t ever had spotting before- and then after 2-3 days of spotting, it stopped. The thing that make me stop taking the medication was (after 9 ish days of awful sleep and increased anxiety), on day 10, I also had restless legs. It was awful! I’ve never had restless legs before- but as soon as it began, I knew what it was. It was the most unsettling, tingling, strange feeling in my legs. I got up several times, walked, massaged my legs, applied magnesium, rubbed them some more, and finally it eased enough to sleep. I have no idea which ingredient or combo of ingredients affected me… but the rest of the bottle will remain untouched. I was really hoping this would better my sleep and stress, but it definitely did the opposite. Just my experience- yours may not be the same- however, I’d love if anyone experienced the same!
Eddie –
Seems to relieve my anxiety
My anxiety has been very bad. I took this product last night and felt like it calmed me. This morning I think I made my coffee too strong and my anxiety was really bad. I took it again and now feel so much better. I know I need to keep taking to see if it really works like it’s been doing. Hopefully it will I will update later.